This site is intended for UK healthcare professionals
Medscape UK Univadis Logo
Medscape UK Univadis Logo

Beclometasone dipropionate topical


Topical formulations of beclometasone dipropionate.

Drugs List

  • beclometasone 0.025% cream
  • beclometasone 0.025% ointment
  • Therapeutic Indications


    Psoriasis excluding widespread plaque psoriasis



    Apply a thin layer of the cream or ointment over the affected area twice daily. Reduce the application interval if improvement is seen, eventually treatment may be stopped.

    If the condition recurs after cessation of treatment, twice daily applications should be reinstated. If the condition improves the interval can be gradually reduced to a maintenance dose every 3 to 4 days to avoid reoccurrence.


    Children under 1 year
    Acne vulgaris
    Perioral dermatitis
    Skin infection
    Skin ulcer

    Precautions and Warnings


    Careful supervision of patients with psoriasis required
    Use appropriate antimicrobial therapy in infected lesions
    Some formulations contain cetostearyl alcohol
    Some formulations contain propylene glycol
    Breastfeeding: Wash product off breasts prior to breastfeeding infant
    Cleanse skin thoroughly before applying occlusive dressings
    Risk of glaucoma if preparation enters eye
    Adrenal suppression may occur even without occlusion
    Potential for withdrawal symptoms
    Prolonged use may cause atrophic skin changes
    Risk of generalised pustular psoriasis with use of topical corticosteroids
    Some formulations contain chlorocresol, may cause allergic reactions
    Discontinue therapy and use antimicrobials if secondary infection occurs
    Avoid long-term use particularly in infants and children
    Limit use in infants or on face to 5 days and without occlusion
    Advise patient residue on clothing/bedding may cause fire hazard
    Fire hazard: Keep away from naked flames and potential sources of ignition
    Nappy may act as an occlusive dressing

    In most cases the cream preparation is for use on moist or weeping skin where as the ointment is applicable for use on dry, lichenified, or scaly lesions. The correct preparation should be used depending on the patients condition.

    The skin should be cleansed before the application of a fresh dressing. Bacterial infection is encouraged by warm, moist conditions induced by occlusive dressings.

    When treating inflammatory lesions that are infected an appropriate antimicrobial should also be administered. If the infection spreads a discontinuation of beclometasone is required. Antimicrobial agents should then be administered systemically.

    If there is no improvement in 2 to 4 weeks then diagnosis should be reassessed.

    If there is a reoccurence in the days or weeks following successful treatment, especially if spread beyond the initial treatment area, this may be a withdrawal reaction. In this case specialist advice should be sought and the treatment only reapplied with caution.

    Atrophic changes may become more apparent on the face than other parts of the body following long term treatment. This should be especially considered when the patient is being treated for psoriasis, discoid lupus erythematosus, and severe eczema.

    When administered in patients suffering from psoriasis it is possible for the occurrence of rebound relapse, development of tolerance, risk of generalised pustular psoriasis, and systemic toxicity due to impaired barrier function of the skin. It is advised that careful patient supervision is maintained in this group.

    Pregnancy and Lactation


    Use beclometasone with caution during pregnancy.

    The manufacturer does not recommend using beclometasone during pregnancy.

    Available reports indicate no increased risk of teratogenic or developmental effects (Briggs 2015). Schaefer (2015) states it has been used extensively in pregnant women and has a good safety record.


    Use beclometasone with caution during breastfeeding.

    The manufacturer does not recommend breastfeeding while using beclometasone.

    It is not known whether topical administration of corticosteroids would result in sufficient systemic absorption to produce detectable quantities in breast milk.

    Studies of breastfed infants exposed to beclometasone have shown no adverse effects. (LactMed 2020)

    When drug administration is unavoidable and breastfeeding is to continue, minimisation of exposure to the infant may sometimes be achieved by timing maternal doses to just after a feeding episode. If the cream is used on the nipple, it should be washed off before breastfeeding and re-applied later.

    Side Effects

    Exacerbation of symptoms
    Hypersensitivity reactions
    Impaired adrenal function
    Local atrophic changes
    Pustular psoriasis
    Secondary infections
    Skin pigmentation changes
    Superficial vascular dilation
    Thinning of skin


    It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.

    The following number will direct the caller to the relevant local centre (0844) 892 0111

    Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( ) or if this is unavailable at the backup site ( ).

    Further Information

    Last Full Review Date: July 2022

    Reference Sources

    Drugs During Pregnancy and Lactation: Treatment Options and Risk Assessment, 3rd edition (2015) ed. Schaefer, C., Peters, P. and Miller, R. Elsevier, London.

    Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk, 10th edition (2015) ed. Briggs, G., Freeman, R. and Yaffe, S. Lippincott Williams & Wilkins, Philadelphia.

    Summary of Product Characteristics: Beclometasone dipropionate 0.25 mg/g cream. Essential Generics. Revised June 2022.
    Summary of Product Characteristics: Beclometasone dipropionate 0.25 mg/g ointment. Essential Generics. Revised June 2022.

    US National Library of Medicine. Toxicology Data Network. Drugs and Lactation Database (LactMed).
    Available at:
    Beclometasone. Last revised: 20 April 2020
    Last accessed: 12 July 2022

    Access the full UK drug database with a FREE Medscape UK Account
    It takes just a few minutes, and you’ll get unlimited access to information on over 11,000 UK drugs.
    Register for Free

    Already a member? Log in

    Medscape UK | Univadis prescription drug monographs & interactions are based on FDB Multilex Content

    FDB Logo

    FDB Disclaimer : FDB Multilex is intended for the use of healthcare professionals and is provided on the basis that the healthcare professionals will retain FULL and SOLE responsibility for deciding what treatment to prescribe or dispense for any particular patient or circumstance.