Betamethasone valerate transdermal medicated plaster
- Drugs List
- Therapeutic Indications
- Dosage
- Contraindications
- Precautions and Warnings
- Pregnancy and Lactation
- Side Effects
- Monograph
Presentation
Medicated plaster formulation of betamethasone valerate.
Drugs List
Therapeutic Indications
Uses
Inflammatory skin conditions unresponsive to less potent corticosteroids
Plaque psoriasis
Dosage
Adults
Apply 1 medicated plaster to the skin area to be treated once daily.
The maximum daily dose is 6 medicated plasters (wait at least 30 minutes between one application and the next) and the maximum treatment period should not exceed 30 days.
Contraindications
Burns
Children under 18 years
Acne vulgaris
Exudative dermatosis
Frostbite
Perioral dermatitis
Rosacea
Skin infection
Skin manifestation of tuberculosis
Skin ulcer
Precautions and Warnings
Breastfeeding
Pregnancy
Careful supervision of patients with psoriasis required
Contains hydroxybenzoate
Avoid occlusive dressings
Cleanse and dry skin before application
Do not apply on or near breasts
Not to be applied to the face
Prolonged use may cause atrophic skin changes
Prolonged/excessive use may lead to adrenal suppression
Risk of generalised pustular psoriasis with use of topical corticosteroids
Withdraw gradually after long-term use
Withdraw gradually if adrenal suppression suspected
Discontinue if hypersensitivity reactions occur
Pregnancy and Lactation
Pregnancy
Use betamethasone valerate medicated plaster with caution during pregnancy.
The manufacturer notes that this medication should only be considered if the expected benefit to the mother is greater than any risk to the foetus, also taking into account the evaluation of the treatment period and the size of the skin area to be treated.
Topical steroids must not be used on large areas of skin or for long periods of time during pregnancy. Topical administration of corticosteroids in pregnant laboratory animals may result in the impairment of foetal development.
Lactation
Use betamethasone valerate medicated plaster with caution during breastfeeding.
The manufacturer notes that this medication should only be considered if the expected benefit to the mother is greater than any risk to the breastfed infant.
Although it is not known if topical corticosteroids are excreted in human milk, systemic corticosteroids are excreted.
Counselling
After application of plaster, do not allow skin to come in contact with water.
If edges of plaster start to lift, apply adhesive strips to secure.
Side Effects
Cushing's syndrome
Erosion
Erythema
Formation of pustules
Furuncle
Papules
Pruritus
Skin atrophy
Suppression of the hypothalamic-pituitary-adrenal axis
Telangiectasia
Overdosage
It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.
The following number will direct the caller to the relevant local centre (0844) 892 0111
Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( www.toxbase.org ) or if this is unavailable at the backup site ( www.toxbasebackup.org ).
Further Information
Last Full Review Date: January 2019
Medscape UK | Univadis prescription drug monographs & interactions are based on FDB Multilex Content

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