Betaxolol hydrochloride ocular with preservative
- Drugs List
- Therapeutic Indications
- Precautions and Warnings
- Pregnancy and Lactation
- Side Effects
Eye drops containing betaxolol (preservative containing).
Treatment of elevated intraocular pressure in chronic open-angle glaucoma
Treatment of elevated intraocular pressure in ocular hypertension
Instil 1 drop into the affected eye(s) twice daily.
Instil 1 drop into the affected eye(s) twice daily (unlicensed).
Sinus node dysfunction
Second degree atrioventricular block
Severe chronic obstructive pulmonary disease
Sinoatrial exit block
Third degree atrioventricular block
Uncontrolled cardiac failure
Precautions and Warnings
Children under 18 years
History of allergies including anaphylaxis
Soft contact lenses
First degree atrioventricular block
History of bronchospasm
Obstructive pulmonary disease
Severe peripheral circulatory disorder
Advise diabetic patients that hypoglycaemic symptoms may be reduced/altered
Give concurrent miotic treatment if used to treat narrow angle glaucoma
May mask symptoms of hyperthyroidism
May unmask the symptoms of myasthenia gravis
Advise ability to drive/operate machinery may be affected by side effects
Advise patient blurred vision may affect ability to drive/operate machinery
Contains benzalkonium chloride. Not to be used with soft contact lenses
In combined therapy, administer eye products at least five minutes apart
To reduce systemic absorption compress lacrimal sac during administration
Monitor patient with history of severe cardiac disease for signs of failure
Beta blockers may reduce the response to adrenaline in anaphylaxis
Systemic absorption & adverse effects of systemic beta blockers may occur
Consider gradual withdrawal of treatment prior to general anaesthesia
Do not withdraw this drug suddenly
Discontinue at the first signs of cardiac failure
Not licensed for use in children under 18 years
Advise patient to avoid touching the eye/other surfaces with container tip
If soft contact lenses worn,insert them 15 minutes after using eye drops
Pregnancy and Lactation
Use betaxolol eye drops with caution during pregnancy.
The manufacturer advises that betaxolol eye drops should not be used during pregnancy unless clearly necessary.
The administration of beta-blockers via the oral route may increase a risk of intra-uterine growth retardation and cause signs and symptoms of beta-blockade in the neonate.
Newborns exposed to betaxolol solution should be monitored during the first days of life.
Use betaxolol eye drops with caution during breastfeeding.
The manufacturer advises caution if betaxolol eye drops are used when breastfeeding.
Betaxolol is excreted in breast milk.
When betaxolol is used ophthalmically, plasma levels and subsequent levels in breast milk are likely to be low, but if used during nursing, the infant should be closely observed for hypotension, bradycardia and other signs or symptoms of beta-blockade. Compression of the lacrimal sac after ocular administration may further reduce systemic absorption.
AV conduction disorders
Choroidal detachment (following filtration surgery)
Congestive cardiac failure
Cyanosis of extremities
Decreased corneal sensitivity
Exacerbation of intermittent claudication
Exacerbation of myasthenia gravis
Exacerbation of psoriasis
Increased atrioventricular block
It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.
The following number will direct the caller to the relevant local centre (0844) 892 0111
Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( www.toxbase.org ) or if this is unavailable at the backup site ( www.toxbasebackup.org ).
Last Full Review Date: November 2021
Summary of Product Characteristics: Betoptic 0.25% eye drops, suspension. Novartis Pharmaceuticals UK Limited. Revised January 2021.
Summary of Product Characteristics: Betoptic 0.5% eye drops, solution. Novartis Pharmaceuticals UK Limited. Revised January 2021.
Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk, 10th edition(2015) ed. Briggs, G., Freeman, R. Wolters Kluwer Health, Philadelphia.
US National Library of Medicine. Toxicology Data Network. Drugs and Lactation Database (LactMed).
Available at: https://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT
Betaxolol Last revised: September 2021
Last accessed: 29 November 2021
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Medscape UK | Univadis prescription drug monographs & interactions are based on FDB Multilex Content
FDB Disclaimer : FDB Multilex is intended for the use of healthcare professionals and is provided on the basis that the healthcare professionals will retain FULL and SOLE responsibility for deciding what treatment to prescribe or dispense for any particular patient or circumstance.