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Diethylamine salicylate

Drugs List

  • ALGESAL cream
  • diethylamine salicylate 10% cream
  • LLOYDS 10% cream
  • Dosage


    Apply sufficient cream to the painful area, massaging until the cream has been fully absorbed. May be repeated two or three times a day.


    See adult dosage.


    Children over 6 years
    See adult dosage.

    Children under 6 years
    Should only be used on medical advice

    Precautions and Warnings

    Do not apply to cut, abraded or broken skin.

    Should only be used in children under 6 years of age on medical advice.

    Some products contain terpene derivatives (i.e. camphor), which can lower the epileptogenic threshold and, at excessive doses, lead to neurological accidents such as convulsions in infants and children. This product should not used in children who have a history of convulsions.

    Avoid contact with eyes, mucous membranes and sensitive areas of skin.

    Discontinue treatment if excessive irritation or unwanted effects occur.

    Pregnancy - see 'Pregnancy' section

    Breastfeeding - see 'Lactation' section

    Pregnancy and Lactation


    Avoid use during pregnancy unless there is no safer alternative.

    The use of all medication in pregnancy should be avoided whenever possible; particularly in the first trimester. Non-drug treatments should also be considered. When essential, a medication with the best safety record over time should be chosen, employing the lowest effective dose for the shortest possible time. Polypharmacy should be avoided. Teratogens taken in the pre-embryonic period, often quoted as lasting until 14-17 days post-conception, are believed to have an all-or-nothing effect. Where drugs have a short half-life, and when the date of conception is certain, this may allow women to be reassured where drug exposure has occurred within this time frame. Further advice may be available from the UK National Teratology Information Service (NTIS) and through ToxBase, available via password on the internet ( ) or if this is unavailable at the backup site ( ).


    Not recommended for use during breastfeeding. However, the amounts of salicylate excreted in breast milk are negligible.

    Neonates, infants born prematurely, those with low birth weight, those with an unstable gastrointestinal function or who have serious illnesses may require special consideration. For any infant, if a drug is prescribed to the nursing mother, it should be at the lowest practical dose and for the shortest time. When drug administration is unavoidable and breastfeeding is to continue, minimisation of exposure of the infant to the drug may sometimes be achieved by timing the maternal doses to just after a feeding episode. Infants exposed to drugs via breast milk should be monitored for unusual signs or symptoms. Interactions between the drug received by the infant from the mother's milk and medication prescribed for the infant should also be considered, for example, when the drug given to the infant may prevent metabolism of the drug received via breast milk.
    Specialist advice is available from the UK Drugs in Lactation Advisory Service at

    Side Effects

    Skin reactions
    Skin reddening
    Burning sensation (local)


    It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.

    The following number will direct the caller to the relevant local centre (0844) 892 0111

    Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( ) or if this is unavailable at the backup site ( ).

    Shelf Life and Storage

    Storage requirements vary according to brand.

    Reference Sources

    Summary of Product Characteristics: Algesal. Thornton & Ross Limited. Revised November 2008.

    Summary of Product Characteristics: Odour Free Lloyds Cream. Thornton & Ross Limited. Revised December 2010.

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    Medscape UK | Univadis prescription drug monographs & interactions are based on FDB Multilex Content

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    FDB Disclaimer : FDB Multilex is intended for the use of healthcare professionals and is provided on the basis that the healthcare professionals will retain FULL and SOLE responsibility for deciding what treatment to prescribe or dispense for any particular patient or circumstance.