Finasteride tablets 1mg
- Drugs List
- Therapeutic Indications
- Dosage
- Contraindications
- Precautions and Warnings
- Pregnancy and Lactation
- Side Effects
- Monograph
Presentation
Film-coated tablets containing finasteride.
Drugs List
Therapeutic Indications
Uses
Alopecia androgenetica in males
Dosage
Adults
Take 1mg once daily with or without food.
There is no evidence that an increase in dosage will result in increased efficacy and treatment should be continuously assessed. Approximately 3 to 6 months of daily treatment are required before there is a stabilisation of hair loss and continuous use is recommended to sustain the benefit. If treatment ceases, the beneficial effects begin to reverse by 6 months and return to baseline by 9 to 12 months.
Contraindications
Children under 18 years
Females
Galactosaemia
Precautions and Warnings
Glucose-galactose malabsorption syndrome
Hepatic impairment
Lactose intolerance
Contains lactose
Staff: Not to be handled by pregnant staff
Reassess need for continued treatment at regular intervals of 3-6 months
Advise patient to report any breast changes e.g. lumps, pain or discharge
Advise patient to report any new or worsening depression/suicidal ideation
Consider discontinuing if depression develops
PSA assay will be affected by decrease in PSA during treatment
May cause impaired fertility
Male: Use of condoms advised if partner pregnant or may become pregnant
Women should not handle crushed/broken tablets due to risk of absorption
Pregnancy and Lactation
Pregnancy
Finasteride is contraindicated for use in women.
Lactation
Finasteride is contraindicated for use in women.
Side Effects
Angioedema
Anxiety
Breast enlargement
Breast neoplasm
Breast tenderness
Decreased ejaculate volume
Depression
Ejaculation disorders
Erectile dysfunction
Haematospermia
Hypersensitivity reactions
Increases in hepatic enzymes
Infertility
Palpitations
Pruritus
Rash
Reduced libido
Sexual dysfunction (male)
Suicidal tendencies
Testicular pain
Urticaria
Overdosage
It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.
The following number will direct the caller to the relevant local centre (0844) 892 0111
Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( www.toxbase.org ) or if this is unavailable at the backup site ( www.toxbasebackup.org ).
Further Information
Last Full Review Date: November 2019
Reference Sources
Summary of Product Characteristics: Propecia 1mg tablets. Merck Sharp and Dohme Limited. Revised May 2019.
NICE Evidence Services Available at: www.nice.org.uk Last accessed: 26 November 2019
Medscape UK | Univadis prescription drug monographs & interactions are based on FDB Multilex Content
FDB Disclaimer : FDB Multilex is intended for the use of healthcare professionals and is provided on the basis that the healthcare professionals will retain FULL and SOLE responsibility for deciding what treatment to prescribe or dispense for any particular patient or circumstance.