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Levofloxacin ocular


Preservative-containing eye drops containing levofloxacin as levofloxacin hemihydrate.

Drugs List

  • levofloxacin 5mg/ml eye drops
  • OFTAQUIX 5mg/ml eye drops
  • Therapeutic Indications


    Bacterial ocular infection: topical treatment



    Days 1 and 2
    Instil one to two drops into the affected eye(s) every two hours up to 8 times per day whilst awake.

    Days 3, 4 and 5
    Instil one to two drops into the affected eye(s) four times daily.


    Children aged 1 year and over
    Days 1 and 2
    Instil one to two drops into the affected eye(s) every two hours up to 8 times per day whilst awake.

    Days 3, 4 and 5
    Instil one to two drops into the affected eye(s) four times daily.


    Children under 1 year
    Wearing of contact lenses

    Precautions and Warnings


    Advise patient blurred vision may affect ability to drive/operate machinery
    Contains benzalkonium chloride
    Administer other ophthalmic products at least 15 minutes apart
    To reduce systemic absorption compress lacrimal sac during administration
    Discontinue at the first sign of tendon inflammation
    Prolonged use may result in superinfection with non-susceptible organisms
    Discontinue if allergic reaction occurs
    Discontinue treatment if any infection worsens
    Advise patient to avoid touching the eye/other surfaces with container tip
    Contact lenses should not be worn during treatment

    Pregnancy and Lactation


    Use levofloxacin eye drops with caution during pregnancy.

    The manufacturer recommends levofloxacin eye drops are not used during pregnancy unless the potential benefit to the mother outweighs the potential risk to the foetus. Animal studies do not indicate any direct or indirect harmful effects relating to reproductive toxicity. At the time of writing there is limited human data available. Risks are unknown.


    Use levofloxacin eye drops with caution during breastfeeding.

    The manufacturer advises levofloxacin is excreted in human milk and should only be used during breastfeeding if the potential benefit justifies any risk to the breast fed child. However, at therapeutic doses of levofloxacin eye drops no effects on the breast fed child are anticipated.

    Side Effects

    Allergic reaction
    Blurred vision (transient)
    Conjunctival chemosis
    Conjunctival follicles
    Dry eyes
    Eyelid erythema
    Eyelid oedema
    Laryngeal oedema
    Lid margin crusting
    Mucous strand
    Ocular burning
    Ocular discomfort
    Ocular itching
    Ocular pain
    Papillary hypertrophy
    Reddening of eyes
    Tendon inflammation
    Tendon rupture


    It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.

    The following number will direct the caller to the relevant local centre (0844) 892 0111

    Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( ) or if this is unavailable at the backup site ( ).

    Further Information

    Last Full Review Date: December 2019

    Reference Sources

    Summary of Product Characteristics: Oftaquix 5mg/ml eye drops, solution. Santen Oy. Revised October 2019.

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    Medscape UK | Univadis prescription drug monographs & interactions are based on FDB Multilex Content

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    FDB Disclaimer : FDB Multilex is intended for the use of healthcare professionals and is provided on the basis that the healthcare professionals will retain FULL and SOLE responsibility for deciding what treatment to prescribe or dispense for any particular patient or circumstance.