Levofloxacin ocular
- Drugs List
- Therapeutic Indications
- Dosage
- Contraindications
- Precautions and Warnings
- Pregnancy and Lactation
- Side Effects
- Monograph
Presentation
Preservative-containing eye drops containing levofloxacin as levofloxacin hemihydrate.
Drugs List
Therapeutic Indications
Uses
Bacterial ocular infection: topical treatment
Dosage
Adults
Days 1 and 2
Instil one to two drops into the affected eye(s) every two hours up to 8 times per day whilst awake.
Days 3, 4 and 5
Instil one to two drops into the affected eye(s) four times daily.
Children
Children aged 1 year and over
Days 1 and 2
Instil one to two drops into the affected eye(s) every two hours up to 8 times per day whilst awake.
Days 3, 4 and 5
Instil one to two drops into the affected eye(s) four times daily.
Contraindications
Children under 1 year
Wearing of contact lenses
Precautions and Warnings
Breastfeeding
Pregnancy
Advise patient blurred vision may affect ability to drive/operate machinery
Contains benzalkonium chloride
Administer other ophthalmic products at least 15 minutes apart
To reduce systemic absorption compress lacrimal sac during administration
Discontinue at the first sign of tendon inflammation
Prolonged use may result in superinfection with non-susceptible organisms
Discontinue if allergic reaction occurs
Discontinue treatment if any infection worsens
Advise patient to avoid touching the eye/other surfaces with container tip
Contact lenses should not be worn during treatment
Pregnancy and Lactation
Pregnancy
Use levofloxacin eye drops with caution during pregnancy.
The manufacturer recommends levofloxacin eye drops are not used during pregnancy unless the potential benefit to the mother outweighs the potential risk to the foetus. Animal studies do not indicate any direct or indirect harmful effects relating to reproductive toxicity. At the time of writing there is limited human data available. Risks are unknown.
Lactation
Use levofloxacin eye drops with caution during breastfeeding.
The manufacturer advises levofloxacin is excreted in human milk and should only be used during breastfeeding if the potential benefit justifies any risk to the breast fed child. However, at therapeutic doses of levofloxacin eye drops no effects on the breast fed child are anticipated.
Side Effects
Allergic reaction
Anaphylaxis
Blurred vision (transient)
Conjunctival chemosis
Conjunctival follicles
Dry eyes
Eyelid erythema
Eyelid oedema
Headache
Laryngeal oedema
Lid margin crusting
Mucous strand
Ocular burning
Ocular discomfort
Ocular itching
Ocular pain
Papillary hypertrophy
Photophobia
Rash
Reddening of eyes
Rhinitis
Tendon inflammation
Tendon rupture
Overdosage
It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.
The following number will direct the caller to the relevant local centre (0844) 892 0111
Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( www.toxbase.org ) or if this is unavailable at the backup site ( www.toxbasebackup.org ).
Further Information
Last Full Review Date: December 2019
Reference Sources
Summary of Product Characteristics: Oftaquix 5mg/ml eye drops, solution. Santen Oy. Revised October 2019.
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