- Drugs List
- Therapeutic Indications
- Precautions and Warnings
- Pregnancy and Lactation
- Side Effects
Topical formulation of lidocaine.
Topical anaesthesia for moderate acute pain during cervical and intrauterine procedures.
Apply 2ml to 3ml in a thick layer to the portio using the sterile applicator, and 3ml into the cervical canal 5 minutes before the start of the procedure.
Apply 1ml to 2ml to the anterior lip of the portio and 2ml to 3ml into the cervical canal using the sterile applicator. After 2 minutes, insert the applicator into the uterine cavity and apply 3ml to 5ml, 5 minutes before the procedure. A single intrauterine dose should not exceed a total of 10ml.
Children aged 15 years and over and weighing over 30kg
(See Dosage; Adult)
Children aged 15 years and over and weighing 30kg or less
1.2ml per 10kg body weight. Maximum dose is 3.6ml in total.
Children under 15 years
Precautions and Warnings
Children aged 15 to 18 years
Contains butylated hydroxytoluene - May irritate skin/eyes/mucous membranes
Contains castor oil polyoxyl - may cause severe allergic reactions
Avoid accidental intravascular injection
In the event of difficult insertion of intrauterine contraceptives and/or exceptional pain or bleeding during or following insertion, physical examination and ultrasound should be performed immediately to rule out perforation of the uterine corpus or cervix.
Pregnancy and Lactation
Use topical lidocaine with caution during pregnancy.
The manufacturer advises caution if topical lidocaine is used during pregnancy. At the time of writing there is limited published information regarding the use of topical lidocaine during pregnancy. Potential risks are unknown.
Parenteral lidocaine should be used with caution during breastfeeding but topical lidocaine is considered safe for use during breastfeeding.
The manufacturer states topical lidocaine may be used safely when breastfeeding. Whilst available data indicates that topical lidocaine is present in human breast milk, the quantity is not considered to be sufficient to cause adverse effects in the breastfed infant.
It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.
The following number will direct the caller to the relevant local centre (0844) 892 0111
Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( www.toxbase.org ) or if this is unavailable at the backup site ( www.toxbasebackup.org ).
Last Full Review Date: December 2022
Summary of Product Characteristics: Lidbree 42mg/ml intrauterine gel. Gedeon Richter (UK) Ltd. Revised July 2021.
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Medscape UK | Univadis prescription drug monographs & interactions are based on FDB Multilex Content
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