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Magnesium sulfate with sodium bicarbonate and citric acid

Presentation

Effervescent powder containing:
Sodium bicarbonate 22.6% w/w
Citric acid 19.5% w/w
Magnesium Sulfate 17.4% w/w

Drugs List

  • ANDREWS ORIGINAL SALTS powder
  • Dosage

    Adults

    Dyspepsia
    One level spoonful (5ml) to be taken in water up to a maximum of four times a day

    Constipation
    Two level spoonfuls (10mls) to be taken in water before breakfast or at bedtime

    Elderly

    See adult dose, however, should be used with caution in this age group

    Children

    Children over 3 years

    Dyspepsia
    2.5ml to be taken in water up to a maximum of four times a day.

    Constipation
    5ml to be taken in water before breakfast or at bedtime.

    Children under 3 years
    Not recommended for this age group.

    Patients with Renal Impairment

    Avoid or decrease dose in moderate renal impairment. Increased risk of toxicity.

    Excessive use in patients with severe renal dysfunction may lead to hypermagnesaemia and hypercalcaemia.

    Precautions and Warnings

    Should be used with caution in patients with the following:
    Renal impairment
    Hepatic impairment
    Cardiac impairment
    Hypochlorhydria
    Hypocalcaemia
    Respiratory alkalosis
    Metabolic alkalosis
    Aldosteronism
    Oedema
    Hypertension
    Eclampsia
    Restricted sodium intake

    Elderly or debilitated patients.

    If daily use is required, investigate the cause of symptoms and advise the patient to consult a doctor if symptoms persist despite treatment

    Avoid frequent use, frequent use in patients with severe renal dysfunction may lead to hypermagnesaemia and hypercalcaemia.

    Preparation contains sucrose, prescribe with caution to patients with glucose-galactose malabsorption syndrome.

    Side Effects

    Abdominal cramps
    Colic
    Gastro-intestinal discomfort
    Diarrhoea
    Belching
    Flatulence

    Overdosage

    It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.

    The following number will direct the caller to the relevant local centre (0844) 892 0111

    Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( https://www.toxbase.org/ ) or if this is unavailable at the backup site ( https://www.TOXBASEbackup.org/ ).

    Pharmacological Properties

    Shelf Life and Storage

    Store below 25 degrees C
    Protect from strong odours

    Reference Sources

    British National Formulary, 58th Edition (2009) Pharmaceutical Press, London.

    Martindale: The Complete Drug Reference, 36th edition (2009) ed. Sweetman, S. Pharmaceutical Press, London.

    Summary of Product Characteristics: Original Andrews Salts, GlaxoSmithKline, October 2006

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    Medscape UK | Univadis prescription drug monographs & interactions are based on FDB Multilex Content

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    FDB Disclaimer : FDB Multilex is intended for the use of healthcare professionals and is provided on the basis that the healthcare professionals will retain FULL and SOLE responsibility for deciding what treatment to prescribe or dispense for any particular patient or circumstance.