Mizolastine tablets 10mg
- Drugs List
- Therapeutic Indications
- Precautions and Warnings
- Pregnancy and Lactation
- Side Effects
Oral formulations of mizolastine.
Seasonal and perennial allergic rhino-conjunctivitis
10mg once a day.
Children aged 12 years and over
10mg once a day.
Children under 12 years
History of cardiac arrhythmias
Long QT syndrome
Severe cardiac dysfunction
Severe hepatic impairment
Torsade de pointes
Precautions and Warnings
Family history of long QT syndrome
Glucose-galactose malabsorption syndrome
History of torsade de pointes
Correct electrolyte disorders before treatment
Advise ability to drive/operate machinery may be affected by side effects
Contains castor oil - may cause adverse gastrointestinal effects
Consider monitoring ECG in patients at risk of QT prolongation
Monitor serum electrolytes
Pregnancy and Lactation
Mizolastine is contraindicated during pregnancy.
The manufacturer does not recommended the use of mizolastine during pregnancy, particularly during the first trimester.
Animal studies do not indicate harmful effects regarding the development of the embryo or foetus, the course of gestation and peri and post natal development.
Mizolastine is contraindicated during breastfeeding.
The manufacturer does not recommended breastfeeding whilst taking mizolastine. Available data indicates mizolastine is expressed in human breast milk, but the quantity is unknown.
Aggravation of existing asthma
Blood sugar changes
Increases in hepatic enzymes
Low neutrophil count
Prolongation of QT interval
It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.
The following number will direct the caller to the relevant local centre (0844) 892 0111
Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( www.toxbase.org ) or if this is unavailable at the backup site ( www.toxbasebackup.org ).
Last Full Review Date: May 2021
Drugs During Pregnancy and Lactation: Treatment Options and Risk Assessment, 3rd edition (2015) ed. Schaefer, C., Peters, P. and Miller, R. Elsevier, London.
Summary of Product Characteristics: Mizollen 10mg modified release tablets. Sanofi Aventis. Revised September 2019.
NICE Evidence Services Available at: www.nice.org.uk Last accessed: 10 May 2021.
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