- Drugs List
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Eye drops containing netilmicin.
Bacterial ocular infection: topical treatment
Treatment of external infections of the eye and its adnexa caused by netilmicin sensitive bacteria.
Instil 1 or 2 drops into the conjunctival sac of the affected eye(s) 3 times daily, or according to medical prescription.
Treatment duration is 5 days. The doctor may recommend a longer treatment in the case of refractory or complicated infections.
Children under 18 years
Precautions and Warnings
Advise patient blurred vision may affect ability to drive/operate machinery
Consult national/regional policy on the use of anti-infectives
In combined therapy, administer eye products at least five minutes apart
To reduce systemic absorption compress lacrimal sac during administration
Prolonged use may result in infection due to resistant organisms
Advise patient to avoid touching the eye/other surfaces with container tip
Advise patient to consult physician if condition worsens / does not improve
Contact lenses should not be worn during treatment
Serious adverse reactions including neurotoxicity, ototoxicity and nephrotoxicity have occurred in patients receiving systemic aminoglycoside therapy. Caution is advised when used concomitantly.
According to the MHRA/CHM advice, there is an increased risk of ototoxicity when aminoglycosides are administered to patients with mitochondrial mutations, including cases where the patient's aminoglycoside serum levels were within the recommended age. Monitor renal, auditory function, hepatic and laboratory parameters to reduce the risks of adverse reactions.
Pregnancy and Lactation
Use netilmicin with caution during pregnancy.
The manufacturer advises that netilmicin should be administered only after a careful benefit-risk assessment and under strict control. Preclinical studies show no foetal toxicity with topical administration of netilmicin.
Netilmicin is contraindicated during breastfeeding.
The manufacturer does not recommend breastfeeding whilst taking netilmicin. Aminoglycosides are excreted in breast milk in small amounts. Effects on exposed infants are unknown.
It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.
The following number will direct the caller to the relevant local centre (0844) 892 0111
Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( www.toxbase.org ) or if this is unavailable at the backup site ( www.toxbasebackup.org ).
Last Full Review Date: June 2022
Summary of Product Characteristics: Nettacin 3mg/ml eye drops. ParaPharm Development Limited. Revised March 2021.
NICE Evidence Services Available at: www.nice.org.uk Last accessed: 27 September 2022
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Medscape UK | Univadis prescription drug monographs & interactions are based on FDB Multilex Content
FDB Disclaimer : FDB Multilex is intended for the use of healthcare professionals and is provided on the basis that the healthcare professionals will retain FULL and SOLE responsibility for deciding what treatment to prescribe or dispense for any particular patient or circumstance.