Nystatin and chlorhexidine and hydrocortisone cream
- Drugs List
- Therapeutic Indications
- Dosage
- Contraindications
- Precautions and Warnings
- Pregnancy and Lactation
- Side Effects
- Monograph
Presentation
Cream containing nystatin, chlorhexidine acetate and hydrocortisone.
Drugs List
Therapeutic Indications
Uses
Infected dermatoses responsive to topical corticosteroids
Dosage
Adults
1 application to infected area one to three times daily.
Maximum treatment duration should be 7 days.
Children
1 application to infected area one to three times daily.
Maximum treatment duration should be 5 to 7 days.
Contraindications
Acne vulgaris
Rosacea
Skin manifestation of tuberculosis
Widespread plaque psoriasis
Precautions and Warnings
Occlusive dressings
Breastfeeding
Pregnancy
Contains benzyl alcohol
Contains polysorbate
Some formulations contain cetostearyl alcohol
Avoid contact with eyes
Avoid contact with mucous membranes
Avoid prolonged application to the face
Prolonged/excessive use may lead to adrenal suppression
Discontinue if sensitisation occurs
Discontinue if superinfection occurs
Avoid long-term use particularly in infants and children
Treatment should be for a maximum period of 7 days
Nappy may act as an occlusive dressing
Pregnancy and Lactation
Pregnancy
Use nystatin, chlorhexidine and hydrocortisone with caution during pregnancy.
The manufacturer advises that the benefit of treatment must outweigh potential risks to the infant.
Lactation
Use nystatin, chlorhexidine and hydrocortisone with caution during breastfeeding.
Side Effects
Acne (at application site)
Adrenal suppression
Anaphylactic shock
Blisters (application site)
Contact dermatitis
Cushing's syndrome
Eczema
Erythema
Exacerbation of infection
Hypersensitivity reactions
Hypertrichosis
Irritation at application site
Itching
Local burning
Perioral dermatitis
Pruritus
Rash
Skin depigmentation
Skin irritation
Striae (irreversible)
Telangiectasia
Thinning of skin
Urticaria
Overdosage
It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.
The following number will direct the caller to the relevant local centre (0844) 892 0111
Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( www.toxbase.org ) or if this is unavailable at the backup site ( www.toxbasebackup.org ).
Further Information
Last Full Review Date: October 2021
Reference Sources
Summary of Product Characteristics: Nystaform HC Cream Typham Ltd. Revised August 2021.
Summary of Product Characteristics: Nystatin/Chlorhexidine hydrochloride/Hydrocortisone 100,000Units/g/1%/0.5% Cream. Typham Ltd. Revised January 2016.
Medscape UK | Univadis prescription drug monographs & interactions are based on FDB Multilex Content
FDB Disclaimer : FDB Multilex is intended for the use of healthcare professionals and is provided on the basis that the healthcare professionals will retain FULL and SOLE responsibility for deciding what treatment to prescribe or dispense for any particular patient or circumstance.