Nystatin with chlorhexidine hydrochloride topical
- Drugs List
- Therapeutic Indications
- Dosage
- Contraindications
- Precautions and Warnings
- Pregnancy and Lactation
- Side Effects
- Monograph
Presentation
Topical formulation of nystatin with chlorhexidine hydrochloride.
Drugs List
Therapeutic Indications
Uses
Bacterial skin infections
Fungal infection of skin
Dosage
Adults
Apply to the affected area 2 to 3 times daily. Continue for 7 days after healing.
If the condition does not improve within 14 days of treatment, an alternative treatment should be substituted.
Children
Apply to the affected area 2 to 3 times daily. Continue for 7 days after healing.
If the condition does not improve within 14 days of treatment, an alternative treatment should be substituted.
Contraindications
None known
Precautions and Warnings
Pregnancy
Contains benzyl alcohol
Contains cetostearyl alcohol: may cause irritation
Contains polysorbate
Avoid contact with eyes
Avoid contact with mucous membranes
Continue treatment for 7 days after signs of infection have resolved
Discontinue if hypersensitivity reactions occur
Discontinue treatment if any infection worsens
Advise patient to see doctor if symptoms persist for 7 days with treatment
Pregnancy and Lactation
Pregnancy
Use nystatin with chlorhexidine hydrochloride with caution during pregnancy.
The manufacturer recommends caution if nystatin with chlorhexidine hydrochloride is used during the early months of pregnancy. The benefit of treatment must outweigh the possible risks.
Lactation
Nystatin with chlorhexidine hydrochloride is considered safe for use during breastfeeding.
Side Effects
Allergic reaction
Anaphylactic shock
Application site reaction
Blisters (application site)
Burning sensation (local)
Dermatitis
Eczema
Erythema
Hypersensitivity reactions
Pruritus
Rash
Skin irritation
Urticaria
Overdosage
It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.
The following number will direct the caller to the relevant local centre (0844) 892 0111
Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( www.toxbase.org ) or if this is unavailable at the backup site ( www.toxbasebackup.org ).
Further Information
Last Full Review Date: October 2016
Reference Sources
Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk, 10th edition (2015) ed. Briggs, G., Freeman, R. Wolters Kluwer Health, Philadelphia.
Summary of Product Characteristics: Nystaform Cream. Typharm Limited. Revised November 2020.
NICE Evidence Services Available at: www.nice.org.uk Last accessed: 03 November 2021
Medscape UK | Univadis prescription drug monographs & interactions are based on FDB Multilex Content
FDB Disclaimer : FDB Multilex is intended for the use of healthcare professionals and is provided on the basis that the healthcare professionals will retain FULL and SOLE responsibility for deciding what treatment to prescribe or dispense for any particular patient or circumstance.