Phenazone with lidocaine auricular
- Drugs List
- Therapeutic Indications
- Dosage
- Contraindications
- Precautions and Warnings
- Pregnancy and Lactation
- Side Effects
- Monograph
Presentation
Ear drops containing phenazone with lidocaine.
Drugs List
Therapeutic Indications
Uses
Acute otitis media
Treatment and relief of pain in the following diseases of the middle ear without tympanic perforation:
Acute, congestive otitis media;
Otitis in influenza;
Barotraumatic otitis.
Dosage
Adults
Instil 4 drops two or three times daily into the affected ear.
If symptoms do not improve 7 days or worsen rapidly or significantly, the therapy should be re-evaluated.
Children
Instil 4 drops two or three times daily into the affected ear.
If symptoms do not improve 7 days or worsen rapidly or significantly, the therapy should be re-evaluated.
Contraindications
Perforated tympanic membrane
Precautions and Warnings
Children under 3 months
G6PD deficiency
Haemoglobinopathies
Exclude tympanic membrane perforation before initiating treatment
Advise patient to report any ear pain, discharge or infection
May affect results of some laboratory tests
If symptoms worsen or persist for more than 7 days, consult a doctor
Cases of methemoglobinemia have been observed following the topical use of local anaesthetics. Caution should be used in patients who are susceptible to methemoglobinemia, including infants under 3 months of age and patients with haemoglobinopathies or glucose-6-phosphate dehydrogenase (G6PD) deficiency.
Pregnancy and Lactation
Pregnancy
Phenazone with lidocaine is considered safe for use during pregnancy.
The manufacturer advises phenazone with lidocaine may be used safely during pregnancy at the recommended dosage and therapy duration. It is unknown whether phenazone with lidocaine crosses the placenta.
Lactation
Phenazone with lidocaine is considered safe for use during breastfeeding.
The manufacturer states phenazone with lidocaine may be used safely when breastfeeding at the recommended dosage and therapy duration. It is unknown whether phenazone with lidocaine pass into the breast milk.
Side Effects
Allergic reaction
Hyperaemia
Itching at application site
Maculopapular rash
Overdosage
It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.
The following number will direct the caller to the relevant local centre (0844) 892 0111
Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( www.toxbase.org ) or if this is unavailable at the backup site ( www.toxbasebackup.org ).
Further Information
Last Full Review Date: November 2020
Reference Sources
Summary of Product Characteristics: Otigo 40mg/10mg/g ear drops, solution. Renascience Pharma Ltd. Revised May 2020.
NICE Evidence Services Available at: www.nice.org.uk Last accessed: 08 March 2021
Medscape UK | Univadis prescription drug monographs & interactions are based on FDB Multilex Content
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