Prednisolone sodium phosphate ocular preservative free
- Drugs List
- Therapeutic Indications
- Precautions and Warnings
- Pregnancy and Lactation
- Side Effects
Preservative free eye drops containing prednisolone sodium phosphate.
Eye - non-infected inflammatory conditions
Instil 1 or 2 drops into the eye as required.
Dose is at the discretion of the doctor.
Precautions and Warnings
Advise patient blurred vision may affect ability to drive/operate machinery
Treat and control infections prior to commencing therapy
In combined therapy, administer eye products at least five minutes apart
To reduce systemic absorption compress lacrimal sac during administration
Check ocular lens frequently - risk of cataract formation
Monitor intraocular pressure frequently - risk of steroid glaucoma
Perform eye tests in any patient with vision change/ophthalmologic symptoms
Prolonged or high dose may lead to adrenal suppression
Contains phosphate: Risk of calcification in existing notable cornea damage
Systemic side effects may occur
Withdraw gradually after long-term use
There is an increased risk of adrenal suppression in infants, particularly after prolonged use. In addition, systemic effects may include growth retardation, psychological and behavioural effects in children and adolescents.
Pregnancy and Lactation
Use prednisolone sodium phosphate preservative-free eye drops with precaution during pregnancy.
The manufacturer recommends prednisolone sodium phosphate preservative-free eye drops should be avoided during pregnancy. Animals studies show that topical administration of corticosteroids can cause abnormalities of foetal development, including cleft palate and intrauterine growth retardation. At the time of writing there is limited human data available. There may be a small risk of similar effects in the human foetus.
Use prednisolone sodium phosphate preservative-free eye drops with caution during breastfeeding.
There is insufficient information on the excretion of prednisolone sodium phosphate and its metabolites in human milk. Effects on exposed infants are unknown.
Increased intra-ocular pressure
It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.
The following number will direct the caller to the relevant local centre (0844) 892 0111
Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( www.toxbase.org ) or if this is unavailable at the backup site ( www.toxbasebackup.org ).
Last Full Review Date: October 2019
Summary of Product Characteristics: Minims Prednisolone Sodium Phosphate 0.5% w/v, Eye drops solution. Bausch & Lomb U.K. Limited. Revised May 2017.
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Medscape UK | Univadis prescription drug monographs & interactions are based on FDB Multilex Content
FDB Disclaimer : FDB Multilex is intended for the use of healthcare professionals and is provided on the basis that the healthcare professionals will retain FULL and SOLE responsibility for deciding what treatment to prescribe or dispense for any particular patient or circumstance.