Drugs List

Therapeutic Indications

Uses

Influenza - prophylaxis

Administration

For intramuscular injection only.

Contraindications

Children under 18 years

Precautions and Warnings

Immunosuppression
Predisposition to bleeding complications
Severe febrile conditions
Breastfeeding
Immunodeficiency syndromes
Pregnancy
Thrombocytopenia

Postpone immunisation if there is active or suspected infection
Impaired response possible in immunocompromised patients
Vaccine may not be effective in 100% of patients
Do not mix with other vaccines in the same syringe
Do not use if any signs of precipitate or particulate matter apparent
Record name and batch number of administered product
Resuscitation facilities must be immediately available
Management of cases of shock should follow current medical standards
Follow national immunisation guidelines

Syncope can occur prior to, or following any vaccination as a psychogenic response to the needle injection. Neurological symptoms such as visual disturbances, paraesthesia and tonic-clonic limb movements during recover. To manage syncope, procedures should be in place to prevent falling and injury.

Pregnancy and Lactation

Pregnancy

Use quadrivalent influenza vaccine with caution during pregnancy.

The manufacturer advises an assessment of the risks and benefits by a health care professional should be performed before using quadrivalent influenza vaccine during pregnancy. At the time of writing there is limited published information regarding the use of quadrivalent influenza vaccine during pregnancy. Potential risks are unknown.

Lactation

Use quadrivalent influenza vaccine with caution during breastfeeding.

The manufacturer advises an assessment of the risks and benefits by a health care professional should be performed before using quadrivalent influenza vaccine during breastfeeding. The presence of quadrivalent influenza vaccine in human breast milk and its effect on exposed infants are unknown.

Side Effects

Allergic reaction
Anaphylactic reaction
Arthralgia
Chills
Cough
Dermatitis
Diarrhoea
Dizziness
Fatigue
Fever
Guillain-Barre syndrome
Headache
Hypersensitivity reactions
Influenza-like symptoms
Local pain (injection site)
Local reaction at injection site
Myalgia
Nausea
Oropharyngeal pain
Pruritus
Rash
Shivering
Slight redness of the skin
Swelling (injection site)
Tenderness (injection site)
Urticaria

Presentation

Vaccine containing influenza virus haemagglutinin (HA) proteins.

Drugs List

Therapeutic Indications

Uses

Influenza - prophylaxis

Dosage

Adults

Administration

For intramuscular injection only.

Contraindications

Children under 18 years

Precautions and Warnings

Immunosuppression
Predisposition to bleeding complications
Severe febrile conditions
Breastfeeding
Immunodeficiency syndromes
Pregnancy
Thrombocytopenia

Postpone immunisation if there is active or suspected infection
Impaired response possible in immunocompromised patients
Vaccine may not be effective in 100% of patients
Do not mix with other vaccines in the same syringe
Do not use if any signs of precipitate or particulate matter apparent
Record name and batch number of administered product
Resuscitation facilities must be immediately available
Management of cases of shock should follow current medical standards
Follow national immunisation guidelines

Syncope can occur prior to, or following any vaccination as a psychogenic response to the needle injection. Neurological symptoms such as visual disturbances, paraesthesia and tonic-clonic limb movements during recover. To manage syncope, procedures should be in place to prevent falling and injury.

Pregnancy and Lactation

Pregnancy

Use quadrivalent influenza vaccine with caution during pregnancy.

The manufacturer advises an assessment of the risks and benefits by a health care professional should be performed before using quadrivalent influenza vaccine during pregnancy. At the time of writing there is limited published information regarding the use of quadrivalent influenza vaccine during pregnancy. Potential risks are unknown.

Lactation

Use quadrivalent influenza vaccine with caution during breastfeeding.

The manufacturer advises an assessment of the risks and benefits by a health care professional should be performed before using quadrivalent influenza vaccine during breastfeeding. The presence of quadrivalent influenza vaccine in human breast milk and its effect on exposed infants are unknown.

Side Effects

Allergic reaction
Anaphylactic reaction
Arthralgia
Chills
Cough
Dermatitis
Diarrhoea
Dizziness
Fatigue
Fever
Guillain-Barre syndrome
Headache
Hypersensitivity reactions
Influenza-like symptoms
Local pain (injection site)
Local reaction at injection site
Myalgia
Nausea
Oropharyngeal pain
Pruritus
Rash
Shivering
Slight redness of the skin
Swelling (injection site)
Tenderness (injection site)
Urticaria

Overdosage

It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.

The following number will direct the caller to the relevant local centre (0844) 892 0111

Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( www.toxbase.org ) or if this is unavailable at the backup site ( www.toxbasebackup.org ).

Further Information

Last Full Review Date: May 2021

Reference Sources

Summary of Product Characteristics: Supemtek solution for injection in pre-filled syringe Quadrivalent Influenza Vaccine (recombinant, prepared in cell culture). Sanofi Pasteur. Revised January 2021.