- Drugs List
- Therapeutic Indications
- Precautions and Warnings
- Pregnancy and Lactation
- Side Effects
Oral formulations of rupatadine.
Rhinitis - allergic
The medication can be taken with or without food.
10mg once daily.
Children aged 12 years and over
10mg once daily.
Children aged 2 to 11 years
1mg/ml oral solution
Weighing equal to or more than 25kg: 5mg (5ml) once daily.
Weighing equal to or more than 10kg up to less than 25kg: 2.5mg (2.5ml) once daily.
Children under 2 years
Precautions and Warnings
Children aged 2 to 12 years
Glucose-galactose malabsorption syndrome
Hereditary fructose intolerance
Advise ability to drive/operate machinery may be affected by side effects
Not all formulations are suitable for use in children under 12 years
Oral liquid contains hydroxybenzoate: caution in hypersensitivity
Some formulations contain lactose
Some formulations contain sucrose
May potentiate effect of CNS depressants
Advise patient that the effects of alcohol may be potentiated
Grapefruit juice should not be taken simultaneously
Pregnancy and Lactation
Use rupatadine with caution in pregnancy.
The manufacturer notes that it is preferable to avoid this medication in pregnancy as a precautionary measure.
There is limited data on the use of rupatadine in pregnant women. Animal studies do not indicate any harmful effects either directly or indirectly to the embryonal/foetal development, parturition or postnatal development.
Use rupatadine with caution in breastfeeding.
The manufacturer notes a decision should be made whether to cease breastfeeding or stop taking the medication.
Rupatadine is excreted in animal milk but it is unknown whether rupatadine is excreted into breast milk.
Abnormal liver function
Alanine aminotransferase increased
Aspartate aminotransferase increased
Creatine phosphokinase increased
Upper abdominal pain
It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.
The following number will direct the caller to the relevant local centre (0844) 892 0111
Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( www.toxbase.org ) or if this is unavailable at the backup site ( www.toxbasebackup.org ).
Last Full Review Date: March 2019
Summary of Product Characteristics: Rupatadine 1mg/ml oral solution. Aspire Pharma Ltd. Revised June 2018.
Summary of Product Characteristics: Rupatadine 10mg tablets. Aspire Pharma Ltd. Revised December 2018.
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Medscape UK | Univadis prescription drug monographs & interactions are based on FDB Multilex Content
FDB Disclaimer : FDB Multilex is intended for the use of healthcare professionals and is provided on the basis that the healthcare professionals will retain FULL and SOLE responsibility for deciding what treatment to prescribe or dispense for any particular patient or circumstance.