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Sodium citrate compound enema

Updated 2 Feb 2023 | Osmotic laxatives


Enema containing sodium citrate compound

Drugs List

  • MICOLETTE micro-enema
  • MICRALAX micro-enema
  • sodium citrate compound enema
  • Therapeutic Indications


    Preparation for radiological, endoscopic and surgical procedures on colon



    Administer the contents of one enema rectally.


    Administer the contents of one enema rectally.


    Children 3 to 18 years
    Administer the contents of one enema rectally.

    Children 1 month to 3 years
    Administer the contents of one enema rectally, but only half the length of the nozzle is inserted into the rectum.

    Not all brands are licensed for use in children under 3 years.


    Acute gastrointestinal disorder
    Inflammatory bowel disease

    Precautions and Warnings

    Children aged 1 month to 3 years

    Children under 3 years: nozzle should be inserted to half its length only
    Not all brands are licensed for children under 3 years
    Avoid prolonged use
    Advise patient that enema takes 5-10 minutes to work after administration

    Pregnancy and Lactation


    Sodium citrate compound enema is indicated for use in constipation in obstetrics.


    No special recommendations.


    Administration instructions are as follows:

    1. Lie down on your side with your knees drawn up towards your tummy, or sit on the toilet.
    2. Pull or twist the cap off the tube.
    3. If necessary lubricate nozzle by squeezing a drop of liquid onto the end of the nozzle.
    4. Insert the full length of the nozzle into your back passage.
    5. Gently squeeze the tube until empty.
    6. Keep squeezing tube as you pull the nozzle out (this is to prevent the medicine being drawn back into the tube).
    7. Wait for the laxative to take effect (5 to 10 minutes).

    Side Effects

    Abdominal pain
    Anal irritation
    Diarrhoea/loose stools
    Hypersensitivity reactions
    Rectal discomfort


    It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.

    The following number will direct the caller to the relevant local centre (0844) 892 0111

    Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( ) or if this is unavailable at the backup site ( ).

    Further Information

    Last Full Review Date: November 2016

    Reference Sources

    Joint Formulary Committee. British National Formulary. 72nd ed. London: BMJ Group and Pharmaceutical Press; 2016.

    Paediatric Formulary Committee. BNF for Children 2016-2017. London: BMJ Group, Pharmaceutical Press, and RCPCH Publications; 2016.

    Summary of Product Characteristics: Micolette Micro-enema. Pinewood Laboratories Ltd. Revised June 2015

    Summary of Product Characteristics: Micralax Micro-enema. RPH Pharmaceuticals. Revised May 2015

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