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Sodium cromoglicate oral

Updated 2 Feb 2023 | Food allergy

Presentation

Oral formulations of sodium cromoglicate.

Drugs List

  • NALCROM 100mg capsules
  • sodium cromoglicate 100mg capsules
  • sodium cromoglicate 100mg/5ml oral solution sugar-free 5ml unit dose ampoules
  • Therapeutic Indications

    Uses

    Food allergies

    Dosage

    The optimal dosage will be determined individually for each individual.

    Adults

    Initially 200mg four times daily before meals (or before three meals and once before bedtime).

    If satisfactory control is not established within 2 to 3 weeks, the dosage may be increased up to a maximum of 40mg/kg/day.

    Once therapeutic response has been achieved the dose may be reduced to the minimum required to maintain the patient free from symptoms.

    Children

    Capsules
    Children aged 14 to 18 years
    See Dosage; Adults.

    Children aged 2 to 14 years
    Initially 100mg four times daily before meals (or before three meals and once before bedtime).

    If satisfactory control is not established within 2 to 3 weeks, the dosage may be doubled but should not exceed 40mg/kg/day.

    Once therapeutic response has been achieved the dose may be reduced to the minimum required to maintain the patient free from symptoms.

    Oral solution
    Initially 100mg four times daily before meals (or before three meals and once before bedtime).

    If satisfactory control is not established within 2 to 3 weeks, the dosage may be doubled but should not exceed 40mg/kg/day.

    Once therapeutic response has been achieved the dose may be reduced to the minimum required to maintain the patient free from symptoms.

    Contraindications

    Children under 2 years

    Precautions and Warnings

    Breastfeeding
    Pregnancy

    Pregnancy and Lactation

    Pregnancy

    Sodium cromoglicate should be used with caution during pregnancy.

    The manufacturers recommend that sodium cromoglicate should be used with caution especially during the first trimester. Cumulative experience with sodium cromoglicate suggests that it has no adverse effects on foetal development.

    Lactation

    Sodium cromoglicate should be used with caution during breastfeeding.

    It is not known whether sodium cromoglicate is excreted in breast milk, but it is considered unlikely. There is no data to suggest that sodium cromoglicate has any undesirable effects on the infant.

    Counselling

    Capsules may be swallowed whole or contents dissolved in hot water and diluted with cold water before taking.

    The oral solution should be taken 15 minutes before a meal.

    If an allergic reaction occurs in the mouth to the nutrients that you are allergic to, then rinse your mouth with the solution before swallowing it.

    Side Effects

    Diarrhoea
    Hypersensitivity reactions
    Joint pain
    Nausea
    Rash
    Stomach discomfort
    Vomiting

    Overdosage

    It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.

    The following number will direct the caller to the relevant local centre (0844) 892 0111

    Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( www.toxbase.org ) or if this is unavailable at the backup site ( www.toxbasebackup.org ).

    Further Information

    Last Full Review Date: April 2021

    Reference Sources

    Summary of Product Characteristics: Nalcrom 100mg capsules. Aventis Pharma Ltd. Revised November 2019.

    Summary of Product Characteristics: Sodium cromoglicate 100mg/5ml oral solution. Brown & Burk UK Ltd. Revised May 2018.

    NICE Evidence Services Available at: www.nice.org.uk Last accessed: 16 March 2021.

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