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Vitamins b and c strong im injection

Updated 2 Feb 2023 | Vitamin B group Vitamin C


Pair of ampoules containing:

No1 (5ml ampoule): thiamine hydrochloride 250mg, riboflavin 4mg and pyridoxine hydrochloride 50mg

No2 (2ml ampoule): ascorbic acid 500mg and nicotinamide 160mg.

Drugs List

  • vitamins b and c strong intramuscular injection
  • Therapeutic Indications


    Alcoholism (adjunctive treatment)
    Debility - severe (after major surgery or disease)
    Vitamin B deficiency
    Vitamin C deficiency
    Wernickes encephalopathy

    Rapid correction of severe depletion or malabsorption of vitamins B and C (e.g. in alcoholism, after acute infections, post operatively and in psychiatric states)


    This preparation is also available as an Intravenous Strong Injection. Therefore ensure that the labels of the ampoule are for the desired route before administration.


    The mixed contents of one pair of ampoules (7ml) twice daily for up to 7 days.

    The following alternative dosing schedule may be suitable:
    Prevention of Wernicke's encephalopathy in alcoholism
    One pair once a day for at least 5 days and up to 7 days if required.


    Children aged 14 to 18 years: See Dosage; Adult.
    Children aged 10 to 14 years: One half to two thirds of the adult dose.
    Children aged 6 to 10 years: One third of the adult dose.
    Children under 6 years: One quarter of the adult dose.


    For intramuscular administration into the gluteal muscle only.
    Inject slowly high into the gluteal muscle, 5cm below the iliac crest.


    Hypersensitivity to benzyl alcohol

    Precautions and Warnings

    Children under 3 years
    Restricted sodium intake
    Hepatic impairment
    Renal impairment

    Contains more than 1 mmol (23 mg) sodium per dose
    Contains benzyl alcohol
    Do not use if any signs of precipitate or particulate matter apparent
    Resuscitation facilities must be immediately available
    Use only when parenteral treatment is essential

    For intramuscular administration only. Care should be taken to ensure that the route of administration is the desired before administer the product to the patient.

    Pregnancy and Lactation


    Use vitamins B and C strong intramuscular injection with caution during pregnancy.

    The manufacturer advises caution if vitamins B and C strong intramuscular injection is used during pregnancy. At the time of writing there is limited published information regarding the use of vitamins B and C strong intramuscular injection during pregnancy. Potential risks are unknown.


    Use vitamins B and C strong intramuscular injection with caution during breastfeeding.

    The manufacturer advises caution if vitamins B and C strong intramuscular injection is used when breastfeeding. The presence of vitamins B and C strong intramuscular injection in human breast milk and the effects of exposed infants are unknown.

    Side Effects

    Hypersensitivity reactions
    Local pain (injection site)


    It is strongly recommended that the UK National Poisons Information Service be consulted on cases of suspected or actual overdose where there is doubt over the degree of risk or about appropriate management.

    The following number will direct the caller to the relevant local centre (0844) 892 0111

    Information may be obtained if you have access to ToxBase the primary clinical toxicology database of the National Poisons Information Service. This is available via password on the internet ( ) or if this is unavailable at the backup site ( ).

    Further Information

    Last Full Review Date: January 2020

    Reference Sources

    Summary of Product Characteristics: Pabrinex Intramuscular High Potency Injection. Archimedes Pharma Ltd. Revised July 2018.

    NICE Evidence Services Available at: Last accessed: 16 January 2020

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    Medscape UK | Univadis prescription drug monographs & interactions are based on FDB Multilex Content

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